α,β-Dicarbonyl reduction is mediated by theSaccharomycesOld Yellow Enzyme
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چکیده
منابع مشابه
Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase.
Diketoreductase catalyzes a two-step bioreduction on a dicarbonyl substrate through a novel dual catalysis mode, in which random hydride attack simultaneously forms two mono-carbonyl intermediates, and subsequently distinct catalytic sites are responsible for the reductions of respective carbonyl group of the intermediates to yield the final dihydroxy product.
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ژورنال
عنوان ژورنال: FEMS Yeast Research
سال: 2016
ISSN: 1567-1364,1567-1364
DOI: 10.1093/femsyr/fow059